[唾液腺癌症] 唾液腺癌症簡介

唾液腺癌症在臨床放射治療實務上有時候會碰到, 不過機會不是很多, 但還是要來了解一下, 這邊搭配PEREZ 跟 NCCN guideline 來做個整理!

一. 解剖: 
1. major salivary gland: parotid, submandibular, and sublingual
2. minor salivary gland

二. 流行病學(取自PEREZ)
1.  salivary tumor(良性惡性都有可能): parotid gland: 70%, submandibular: 8%, minor salivary gland: 22%
2. tumor 惡性比例: parotid gland: 25%, submandibular: 43%, minor salivary gland: 65%

三. 自然史:
1. local invasion: 腫瘤侵犯的第一步
2. 對側淋巴侵犯機率極低
3. 脖子淋巴侵犯機率: 
(1) highest risk: squamous cell, undifferentiated cancer, and salivary duct cancer
(2) Intermediate risk: mucoepidermoid cancer 
(3) low risk: acinic cell, adenoid cystic carcinoma, and carcinoma ex pleomorphic adenoma

reference:
1. Perez and Brady's radiation oncology
2. NCCN guideline