[肺癌] ASTRO 2018 palliative radiotherapy guideline

在肺癌的治療裡面, palliative RT 一直是一個重要的角色, ASTRO 針對這個議題, 在2018年的時候推出了準則, 雖然時間已經過去三年, 不過仍然是值得參考的資料, 以下就來細讀吧!

 KQ 1: CCRT 在肺癌palliative setting 的角色?

三期 NSCLC, 不適合curative therapy, 但是符合以下條件

(1) candidates for chemotherapy
(2) have an Eastern Cooperative Oncology Group (ECOG) PS of 0 to 2
(3) have a life expectancy of at least 3 months

=> 可以給palliaitve CCRT

evidence 的話, ASTRO guideline 是依照三篇RCT, 都是palliaitve setting 下去比較CCRT versus RT

Stage IV NSCLC:

沒有證據CCRT可以使用在palliative setting

References:

1. Moeller, B., Balagamwala, E. H., Chen, A., Creach, K. M., Giaccone, G., Koshy, M., Zaky, S., & Rodrigues, G. (2018). Palliative thoracic radiation therapy for non-small cell lung cancer: 2018 Update of an American Society for Radiation Oncology (ASTRO) Evidence-Based Guideline. Practical radiation oncology, 8(4), 245–250. https://doi.org/10.1016/j.prro.2018.02.009