Endometrial cancer
|
Type I
|
Type II
|
Estrogen stimulation
|
Associated
|
Not associated
|
age
|
Premenopausal,
Peri-menopausal
|
Post-menopausal
|
histology
|
Indolent,
Minimal myometrial invasion,
Low grade
|
More advanced,
Deep myometrial invasion,
High grade
(serous or clear cell)
|
Molecular pathway
|
PI3 K/PTEN/AKT pathway
|
tumor suppressors p53
|
reference:
1. Perez and Brady's radiation oncology 7th edition
2. Clinical radiation oncology 5th edition
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